Arsenic 3 methyltransferase (AS3MT) automethylates on cysteine residues in vitro.

Mersaoui, Sofiane Y; Guilbert, Cynthia; Chou, Hsiang; Douillet, Christelle; Bohle, D Scott; Stýblo, Miroslav; Richard, Stéphane; Mann, Koren K

Mersaoui, Sofiane Y; Guilbert, Cynthia; Chou, Hsiang; Douillet, Christelle; Bohle, D Scott; Stýblo, Miroslav; Richard, Stéphane; Mann, Koren K.

Afiliação

Mersaoui SY; Segal Cancer Center, Lady Davis Institute for Medical Research and Departments of Oncology and Medicine, McGill University, Montréal, Québec, H3T 1E2, Canada.
Guilbert C; Segal Cancer Center, Lady Davis Institute for Medical Research and Departments of Oncology and Medicine, McGill University, Montréal, Québec, H3T 1E2, Canada.
Chou H; Segal Cancer Center, Lady Davis Institute for Medical Research and Departments of Oncology and Medicine, McGill University, Montréal, Québec, H3T 1E2, Canada.
Douillet C; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599, USA.
Bohle DS; Department of Chemistry, McGill University, Otto Maass 233A, Montréal, Québec, H3A 0B8, Canada.
Stýblo M; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB# 7461, Chapel Hill, NC, 27599, USA.
Richard S; Segal Cancer Center, Lady Davis Institute for Medical Research and Departments of Oncology and Medicine, McGill University, Montréal, Québec, H3T 1E2, Canada. stephane.richard@mcgill.ca.
Mann KK; Segal Cancer Center, Lady Davis Institute for Medical Research and Departments of Oncology and Medicine, McGill University, Montréal, Québec, H3T 1E2, Canada. koren.mann@mcgill.ca.

Arch Toxicol ; 96(5): 1371-1386, 2022 05.

Article em En | MEDLINE | ID: mdl-35244730

Assuntos

Arsênio; Metiltransferases; Animais; Arsênio/metabolismo; Arsênio/toxicidade; Cisteína; Dissulfetos; Glutationa/metabolismo; Metiltransferases/genética; Metiltransferases/metabolismo; Camundongos; Espectrometria de Massas em Tandem

Palavras-chave

AS3MT; Arsenic; Automethylation; Cysteines; Methyltransferase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arsênio / Metiltransferases Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Arsênio / Metiltransferases Idioma: En Ano de publicação: 2022 Tipo de documento: Article