Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABA<sub>A</sub> activation.

Mu, Jie-Dan; Ma, Liang-Xiao; Zhang, Zhou; Yu, Wen-Yan; Sun, Tian-Yi; Qian, Xu; Tian, Yuan; Wang, Jun-Xiang

Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABA_A activation.

Mu, Jie-Dan; Ma, Liang-Xiao; Zhang, Zhou; Yu, Wen-Yan; Sun, Tian-Yi; Qian, Xu; Tian, Yuan; Wang, Jun-Xiang.

Afiliação

Mu JD; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Ma LX; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China; The Key Unit of State Administration of Traditional Chinese Medicine, Evaluation of Characteristic Acupuncture Therapy, Beijing 100029, China. Electronic address: maliangxiao@vip.sina.com.
Zhang Z; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Yu WY; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Sun TY; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Qian X; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Tian Y; School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.
Wang JX; School of Nursing, Beijing University of Chinese Medicine, Beijing 100029, China.

Exp Neurol ; 354: 114027, 2022 08.

Article em En | MEDLINE | ID: mdl-35245503

Assuntos

Terapia por Acupuntura; AVC Isquêmico; Acidente Vascular Cerebral; Simportadores; Animais; Humanos; Hipertonia Muscular/complicações; Hipertonia Muscular/terapia; Espasticidade Muscular/etiologia; Espasticidade Muscular/metabolismo; Espasticidade Muscular/terapia; Ratos; Receptores de GABA-A; Reflexo Anormal; Acidente Vascular Cerebral/complicações; Acidente Vascular Cerebral/terapia; Simportadores/metabolismo; Ácido gama-Aminobutírico

Palavras-chave

Acupuncture; Gait analysis; H-reflex; Ischemic stroke; KCC2-GABA(AÎ³2); Motor dysfunction; Spastic hypertonia; Spinal Motoneuron

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Terapia por Acupuntura / Acidente Vascular Cerebral / Simportadores / AVC Isquêmico Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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