Tetraphenylethylene-DNA conjugates: influence of sticky ends and DNA sequence length on the supramolecular assembly of AIE-active vesicles.
Org Biomol Chem
; 20(18): 3703-3707, 2022 05 11.
Article
em En
| MEDLINE
| ID: mdl-35262542
ABSTRACT
The supramolecular assembly of DNA conjugates, functionalized with tetraphenylethylene (TPE) sticky ends, into vesicular structures is described. The aggregation-induced emission (AIE) active TPE units allow monitoring the assembly process by fluorescence spectroscopy. The number of TPE modifications in the overhangs of the conjugates influences the supramolecular assembly behavior. A minimum of two TPE residues on each end are required to ensure a well-defined assembly process. The design of the presented DNA-based nanostructures offers tailored functionalization with applications in DNA nanotechnology.
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1
Base de dados:
MEDLINE
Assunto principal:
Estilbenos
/
DNA
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article