Co-delivery of triamcinolone acetonide and verapamil for synergistic treatment of hypertrophic scars via carboxymethyl chitosan and Bletilla striata polysaccharide-based microneedles.

Zhang, Nan; Xue, Lingping; Younas, Ayesha; Liu, Fenfen; Sun, Junhong; Dong, Zhuolin; Zhao, Yongxing

Zhang, Nan; Xue, Lingping; Younas, Ayesha; Liu, Fenfen; Sun, Junhong; Dong, Zhuolin; Zhao, Yongxing.

Afiliação

Zhang N; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China; Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, Henan Province, Zhengzhou 450001, Henan, PR China; Key Laboratory of Advanced Drug Preparation Technologie
Xue L; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
Younas A; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
Liu F; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
Sun J; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
Dong Z; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China.
Zhao Y; Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan, PR China; Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, Henan Province, Zhengzhou 450001, Henan, PR China; Key Laboratory of Advanced Drug Preparation Technologie

Carbohydr Polym ; 284: 119219, 2022 May 15.

Article em En | MEDLINE | ID: mdl-35287918

Assuntos

Quitosana; Cicatriz Hipertrófica; Cicatriz Hipertrófica/tratamento farmacológico; Cicatriz Hipertrófica/patologia; Humanos; Polissacarídeos/farmacologia; Polissacarídeos/uso terapêutico; Triancinolona Acetonida; Verapamil/farmacologia

Palavras-chave

Bletilla striata polysaccharide; Carboxymethyl chitosan; Hydroxypropyl ß-cyclodextrin; Hypertrophic scar; Microneedle; Triamcinolone acetonide; Verapamil

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cicatriz Hipertrófica / Quitosana Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cicatriz Hipertrófica / Quitosana Idioma: En Ano de publicação: 2022 Tipo de documento: Article