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Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19.
Esparza, Thomas J; Chen, Yaozong; Martin, Negin P; Bielefeldt-Ohmann, Helle; Bowen, Richard A; Tolbert, William D; Pazgier, Marzena; Brody, David L.
Afiliação
  • Esparza TJ; The National Institute of Neurological Disorders and Stroke Intramural Research Program, Laboratory of Functional and Molecular Imaging, Bethesda, MD, USA.
  • Chen Y; Center for Neuroscience and Regenerative Medicine, Uniformed Services University, Bethesda, MD, USA.
  • Martin NP; Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc, Bethesda, MD, USA.
  • Bielefeldt-Ohmann H; Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
  • Bowen RA; Viral Vector Core, National Institute of Environmental Health Sciences, NIH/DHHS, NC, USA.
  • Tolbert WD; Neurobiology Laboratory, National Institute of Environmental Health Sciences, NIH/DHHS, NC, USA.
  • Pazgier M; School of Chemistry & Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, Qld, Australia.
  • Brody DL; Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
MAbs ; 14(1): 2047144, 2022.
Article em En | MEDLINE | ID: mdl-35289719
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos de Domínio Único / Anticorpos Amplamente Neutralizantes / SARS-CoV-2 / COVID-19 / Pulmão / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos de Domínio Único / Anticorpos Amplamente Neutralizantes / SARS-CoV-2 / COVID-19 / Pulmão / Anticorpos Antivirais Idioma: En Ano de publicação: 2022 Tipo de documento: Article