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Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.
Biancon, Giulia; Joshi, Poorval; Zimmer, Joshua T; Hunck, Torben; Gao, Yimeng; Lessard, Mark D; Courchaine, Edward; Barentine, Andrew E S; Machyna, Martin; Botti, Valentina; Qin, Ashley; Gbyli, Rana; Patel, Amisha; Song, Yuanbin; Kiefer, Lea; Viero, Gabriella; Neuenkirchen, Nils; Lin, Haifan; Bewersdorf, Joerg; Simon, Matthew D; Neugebauer, Karla M; Tebaldi, Toma; Halene, Stephanie.
Afiliação
  • Biancon G; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA. Electronic address: giulia.biancon@yale.edu.
  • Joshi P; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Zimmer JT; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA; Institute for Biomolecular Design and Discovery, Yale University, West Haven, CT, USA.
  • Hunck T; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Gao Y; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Lessard MD; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
  • Courchaine E; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA.
  • Barentine AES; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.
  • Machyna M; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA.
  • Botti V; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA.
  • Qin A; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Gbyli R; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Patel A; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Song Y; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA; Department of Hematologic Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center
  • Kiefer L; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
  • Viero G; Institute of Biophysics, CNR, Trento, Italy.
  • Neuenkirchen N; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA.
  • Lin H; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA; Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Bewersdorf J; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA; Department of Biomedical Engineering, Yale University, New Haven, CT, USA.
  • Simon MD; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA; Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA; Institute for Biomolecular Design and Discovery, Yale University, West Haven, CT, USA.
  • Neugebauer KM; Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT, USA; Yale Center for RNA Science and Medicine, Yale University School of Medicine, New Haven, CT, USA.
  • Tebaldi T; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA; Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy. Electronic address: toma.tebaldi@unitn.it.
  • Halene S; Section of Hematology, Department of Internal Medicine, Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, CT, USA; Yale Stem Cell Center, Yale University School of Medicine, New Haven, CT, USA; Yale Center for RNA Science and Medicine, Yale University School of Medicin
Mol Cell ; 82(6): 1107-1122.e7, 2022 03 17.
Article em En | MEDLINE | ID: mdl-35303483
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Fator de Processamento U2AF / Grânulos de Estresse Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Fator de Processamento U2AF / Grânulos de Estresse Idioma: En Ano de publicação: 2022 Tipo de documento: Article