Ortho-silicic Acid Plays a Protective Role in Glucocorticoid-Induced Osteoporosis via the Akt/Bad Signal Pathway In Vitro and In Vivo.

Gu, Guanghui; Hou, Dehui; Jiao, Guangjun; Wu, Wenliang; Zhou, Hongming; Wang, Hongliang; Chen, Yunzhen

Gu, Guanghui; Hou, Dehui; Jiao, Guangjun; Wu, Wenliang; Zhou, Hongming; Wang, Hongliang; Chen, Yunzhen.

Afiliação

Gu G; Qilu Hospital of Shandong University, Jinan, Shandong, China.
Hou D; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Jiao G; Qilu Hospital of Shandong University, Jinan, Shandong, China.
Wu W; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Zhou H; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Wang H; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Chen Y; Department of Spine Surgery, Linyi Central Hospital, Linyi, Shandong, China.

Biol Trace Elem Res ; 201(2): 843-855, 2023 Feb.

Article em En | MEDLINE | ID: mdl-35314965

Assuntos

Osteoporose; Animais; Camundongos; Dexametasona/farmacologia; Glucocorticoides/efeitos adversos; Osteoblastos; Osteogênese; Osteoporose/induzido quimicamente; Osteoporose/tratamento farmacológico; Osteoporose/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Ácido Silícico/farmacologia; Silício/farmacologia

Palavras-chave

Apoptosis; GIOP; Ortho-silicic acid; The Akt pathway

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoporose Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteoporose Idioma: En Ano de publicação: 2023 Tipo de documento: Article