c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells.

Pawlowska, Monika; Kulesza, Jolanta; Augustin, Ewa

Pawlowska, Monika; Kulesza, Jolanta; Augustin, Ewa.

Afiliação

Pawlowska M; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, 80-233 Gdansk, Poland.
Kulesza J; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, 80-233 Gdansk, Poland.
Augustin E; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, 80-233 Gdansk, Poland.

Int J Mol Sci ; 23(6)2022 Mar 11.

Article em En | MEDLINE | ID: mdl-35328482

Assuntos

Neoplasias Colorretais; Neoplasias Pulmonares; Apoptose; Linhagem Celular Tumoral; Neoplasias Colorretais/patologia; Células HCT116; Humanos; Pulmão/patologia; Neoplasias Pulmonares/metabolismo; Proteínas Proto-Oncogênicas p21(ras)/genética; Proteínas Proto-Oncogênicas p21(ras)/metabolismo

Palavras-chave

G-quadruplexes; anticancer potential; apoptosis; biological activity; c-Myc; drug discovery; senescence; unsymmetrical bisacridines (UAs)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Neoplasias Pulmonares Idioma: En Ano de publicação: 2022 Tipo de documento: Article