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Massively parallel, computationally guided design of a proenzyme.
Yachnin, Brahm J; Azouz, Laura R; White, Ralph E; Minetti, Conceição A S A; Remeta, David P; Tan, Victor M; Drake, Justin M; Khare, Sagar D.
Afiliação
  • Yachnin BJ; Department of Chemistry & Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • Azouz LR; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • White RE; Department of Chemistry & Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • Minetti CASA; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • Remeta DP; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455.
  • Tan VM; Department of Chemistry & Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • Drake JM; Department of Chemistry & Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
  • Khare SD; Institute for Quantitative Biomedicine, Rutgers, The State University of New Jersey, Piscataway, NJ 08854.
Proc Natl Acad Sci U S A ; 119(15): e2116097119, 2022 04 12.
Article em En | MEDLINE | ID: mdl-35377786
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gama-Glutamil Hidrolase / Desenho de Fármacos / Engenharia de Proteínas / Desenho Assistido por Computador / Precursores Enzimáticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Gama-Glutamil Hidrolase / Desenho de Fármacos / Engenharia de Proteínas / Desenho Assistido por Computador / Precursores Enzimáticos Idioma: En Ano de publicação: 2022 Tipo de documento: Article