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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer.
Jahid, Sohail; Ortega, Jose A; Vuong, Linh M; Acquistapace, Isabella Maria; Hachey, Stephanie J; Flesher, Jessica L; La Serra, Maria Antonietta; Brindani, Nicoletta; La Sala, Giuseppina; Manigrasso, Jacopo; Arencibia, Jose M; Bertozzi, Sine Mandrup; Summa, Maria; Bertorelli, Rosalia; Armirotti, Andrea; Jin, Rongsheng; Liu, Zheng; Chen, Chi-Fen; Edwards, Robert; Hughes, Christopher C W; De Vivo, Marco; Ganesan, Anand K.
Afiliação
  • Jahid S; Department of Dermatology, University of California, Irvine, CA 92697, USA.
  • Ortega JA; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Vuong LM; Department of Dermatology, University of California, Irvine, CA 92697, USA.
  • Acquistapace IM; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Hachey SJ; Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA.
  • Flesher JL; Department of Biological Chemistry, University of California, Irvine, CA 92697, USA.
  • La Serra MA; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Brindani N; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • La Sala G; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Manigrasso J; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Arencibia JM; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Bertozzi SM; Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Summa M; Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Bertorelli R; Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Armirotti A; Analytical Chemistry and Translational Pharmacology, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.
  • Jin R; Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA.
  • Liu Z; Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA.
  • Chen CF; Department of Dermatology, University of California, Irvine, CA 92697, USA.
  • Edwards R; Department of Pathology and Lab Medicine, University of California, Irvine, CA 92697, USA.
  • Hughes CCW; Department of Molecular Biology and Biochemistry, University of California, Irvine, CA 92697, USA.
  • De Vivo M; Laboratory of Molecular Modeling and Drug Design, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy. Electronic address: marco.devivo@iit.it.
  • Ganesan AK; Department of Dermatology, University of California, Irvine, CA 92697, USA; Department of Biological Chemistry, University of California, Irvine, CA 92697, USA. Electronic address: aganesan@uci.edu.
Cell Rep ; 39(1): 110641, 2022 04 05.
Article em En | MEDLINE | ID: mdl-35385746
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Endoteliais / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Endoteliais / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article