Change in parathyroid hormone levels from baseline predicts hypocalcemia following total or completion thyroidectomy.
Head Neck
; 44(7): 1588-1595, 2022 07.
Article
em En
| MEDLINE
| ID: mdl-35396878
ABSTRACT
BACKGROUND:
This study aims to identify the strongest predictor of postoperative hypocalcemia following thyroid surgery.METHODS:
Study of patients who underwent total/completion thyroidectomy. No patients received postoperative calcium supplementation. Demographic and perioperative data were collected including preoperative baseline parathyroid hormone (PTH) levels, PTH levels at 30 min and 6 h post-excision, and 18 h post-excision calcium levels.RESULTS:
Of 124 patients studied, 20.2% developed temporary hypocalcemia (Ca <8.5 mg/dL at 18 h post-excision). In multivariate analyses, absolute PTH levels at 30 min and 6 h post-excision as well as change in PTH from baseline at 30 min and 6 h post-excision were statistically significantly associated with postoperative hypocalcemia. Per 10 units decrease in PTH from baseline at 30 min post-excision, the risk of developing temporary hypocalcemia increases by 17%.CONCLUSION:
Absolute PTH levels and change in PTH from baseline at 30 min and 6 h post-excision predict hypocalcemia after total or completion thyroidectomy.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Hipocalcemia
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article