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Synthesis and Characterization of Titanium Oxide Nanoparticles with a Novel Biogenic Process for Dental Application.
Mansoor, Afsheen; Khan, Muhammad Talal; Mehmood, Mazhar; Khurshid, Zohaib; Ali, Muhammad Ishtiaq; Jamal, Asif.
Afiliação
  • Mansoor A; Department of Microbiology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
  • Khan MT; Department of Dental Material Sciences, School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad 44080, Pakistan.
  • Mehmood M; Department of Dental Biomaterials, Bakhtawar Amin Medical and Dental College, Multan 60650, Pakistan.
  • Khurshid Z; Department of Metallurgy and Materials Engineering, Pakistan Institute of Engineering and Applied Sciences, Islamabad 45650, Pakistan.
  • Ali MI; Department of Prosthodontics and Dental Implantology, College of Dentistry, King Faisal University, Al-Hofuf 31982, Saudi Arabia.
  • Jamal A; Department of Microbiology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Nanomaterials (Basel) ; 12(7)2022 Mar 25.
Article em En | MEDLINE | ID: mdl-35407196
ABSTRACT
The prevalence of dental caries has been largely consonant over time despite the enhancement in dental technologies. This study aims to produce novel GIC restorative material by incorporating TiO2 nanoparticles synthesized by Bacillus subtilis for the treatment of dental caries. The TiO2 nanoparticles were prepared by inoculating a fresh culture of Bacillus subtilis into a nutrient broth for 24 h, which was then characterized by XRD, DRS, FTIR, AFM, SEM, TEM and EDX. These TiO2 nanoparticles were incorporated in GIC restorative material at different concentrations (0-10% TiO2 -GIC) and were tested for their mechanical properties in a universal testing machine. The XRD analysis revealed synthesis of anatase and rutile-phased TiO2 nanoparticles with a particle size of 70.17 nm that was further confirmed by SEM and TEM analysis. The EDX spectrum indicated prominent peaks of titanium and oxygen with no impurities in the prepared material. Treatment with 5% TiO2 -GIC proved to be most effective for the treatment of dental caries with no observable cytotoxic effect. An increase in the compressive strength of TiO2 nanoparticle-reinforced GIC was observed as the concentration of the TiO2 nanoparticles was increased up to 5%; subsequently, the compressive strength was lowered. An increase in the flexural strength was observed in GIC containing 0%, 3% and 5% TiO2 nanoparticles sequentially. Based on the results, it can be concluded that Bacillus subtilis-derived TiO2 nanoparticles have excellent potential for developing next generation of restorative materials for dental issues.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article