Disturbance of neurotransmitter metabolism in drug-naïve, first-episode major depressive disorder: a comparative study on adult and adolescent cohorts.

Wang, Liwei; Yang, Ping; Yang, Chao; Yang, Dong; Wu, Xiangxin; Cao, Ting; Zeng, Cuirong; Chen, Qian; Zhang, Shuangyang; Zhu, Zhenyu; Jiao, Shimeng; Cai, Hualin

Wang, Liwei; Yang, Ping; Yang, Chao; Yang, Dong; Wu, Xiangxin; Cao, Ting; Zeng, Cuirong; Chen, Qian; Zhang, Shuangyang; Zhu, Zhenyu; Jiao, Shimeng; Cai, Hualin.

Afiliação

Wang L; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Yang P; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, Hunan, China.
Yang C; Department of Psychiatry, The Second People's Hospital of Hunan Province, Changsha, 410007, Hunan, China.
Yang D; Department of Child Psychology, Xinjiang Mental Health Center and Urumqi Fourth People's Hospital, Urumqi, 830000, Xinjiang, China.
Wu X; Department of Psychiatry, The Second People's Hospital of Hunan Province, Changsha, 410007, Hunan, China.
Cao T; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Zeng C; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, Hunan, China.
Chen Q; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Zhang S; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, Hunan, China.
Zhu Z; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Jiao S; Institute of Clinical Pharmacy, Central South University, Changsha, 410011, Hunan, China.
Cai H; Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.

Eur Arch Psychiatry Clin Neurosci ; 272(7): 1283-1296, 2022 Oct.

Article em En | MEDLINE | ID: mdl-35410391

Assuntos

Transtorno Depressivo Maior; Cinurenina; Ácido 3,4-Di-Hidroxifenilacético; Adolescente; Adulto; Biomarcadores; Transtorno Depressivo Maior/diagnóstico; Dopamina; Ácido Glutâmico; Glutamina; Ácido Homovanílico; Humanos; Ácido Hidroxi-Indolacético; Ácido Cinurênico; Cinurenina/metabolismo; Metoxi-Hidroxifenilglicol; Neurotransmissores/metabolismo; Norepinefrina; Serotonina; Triptofano; Ácido Vanilmandélico; Ácido gama-Aminobutírico

Palavras-chave

Adolescent; First episode; Major depressive disorder; Neurotransmitter; Tryptophan

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Cinurenina Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transtorno Depressivo Maior / Cinurenina Idioma: En Ano de publicação: 2022 Tipo de documento: Article