Impact of material properties in determining quaternary ammonium compound adsorption and wipe product efficacy against biofilms.
J Hosp Infect
; 126: 37-43, 2022 Aug.
Article
em En
| MEDLINE
| ID: mdl-35427722
ABSTRACT
BACKGROUND:
Disinfectant wipes containing quaternary ammonium compounds (QACs) are widely used within health care. Viscose remains a popular material for these products, although limited information is available concerning its impact on performance against biofilms when compared with alternatives.AIM:
To identify disinfectant wipe materials and surface properties which optimize product performance against biofilms.METHODS:
Biofilm eradication performance of two commercial viscose-QAC wipes was determined against Staphylococcus aureus and Acinetobacter baumannii dry surface biofilms (DSBs) using an ASTM E2967-based procedure. Additionally, five materials were impregnated with a commercial liquid formulation containing didecyldimethylammonium chloride (DDAC). Following 24 h of storage, eradication performance and DDAC content of extracted liquid were determined and compared with material properties, including zeta potential, hydrophobicity and surface area.FINDINGS:
Under stringent test conditions, eradication of DSBs by commercial products was no greater than equivalent materials impregnated with water. Extract from one viscose-based product contained 89% less DDAC than the impregnation solution, indicating extensive adsorption. Of the other tested materials, viscose performed worst; nearly 70% of DDAC had depleted from material extracts within 24 h. In contrast, DDAC depletion from polypropylene extracts was only 25%, and DSB eradication was >100 times greater than viscose. Biofilm eradication performance against both species correlated with the DDAC content of extracts, which, in turn, correlated with zeta potential and hydrophobicity.CONCLUSION:
Biofilm eradication performance of QAC-based wipes was significantly greater when selecting thermoplastic substrates over viscose. However, these materials are non-sustainably sourced and non-biodegradable. This study highlights a need to develop new wipe products that are more effective against biofilms.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Desinfetantes
/
Compostos de Amônio Quaternário
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article