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AKT mutant allele-specific activation dictates pharmacologic sensitivities.
Shrestha Bhattarai, Tripti; Shamu, Tambudzai; Gorelick, Alexander N; Chang, Matthew T; Chakravarty, Debyani; Gavrila, Elena I; Donoghue, Mark T A; Gao, JianJong; Patel, Swati; Gao, Sizhi Paul; Reynolds, Margaret H; Phillips, Sarah M; Soumerai, Tara; Abida, Wassim; Hyman, David M; Schram, Alison M; Solit, David B; Smyth, Lillian M; Taylor, Barry S.
Afiliação
  • Shrestha Bhattarai T; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shamu T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gorelick AN; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chang MT; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chakravarty D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gavrila EI; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Donoghue MTA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Gao J; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Patel S; Loxo Oncology at Lilly, Stamford, CT, USA.
  • Gao SP; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Reynolds MH; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Phillips SM; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Soumerai T; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Abida W; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hyman DM; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Schram AM; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Solit DB; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Smyth LM; Marie-Josee and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Taylor BS; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Commun ; 13(1): 2111, 2022 04 19.
Article em En | MEDLINE | ID: mdl-35440569
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-akt / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article