Biochemical and structural characterization of <i>Haemophilus influenzae</i> nitroreductase in metabolizing nitroimidazoles.

Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.

Liu, Dake; Wanniarachchi, Thisuri N; Jiang, Guangde; Seabra, Gustavo; Cao, Shugeng; Bruner, Steven D; Ding, Yousong.

Afiliação

Liu D; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida Gainesville Florida 32610 USA yding@cop.ufl.edu.
Wanniarachchi TN; Department of Chemistry, University of Florida Gainesville Florida 32611 USA bruner@chem.ufl.edu.
Jiang G; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida Gainesville Florida 32610 USA yding@cop.ufl.edu.
Seabra G; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida Gainesville Florida 32610 USA yding@cop.ufl.edu.
Cao S; Department of Pharmaceutical Sciences, University of Hawai'i at Hilo Hilo Hawaii 96720 USA.
Bruner SD; Department of Chemistry, University of Florida Gainesville Florida 32611 USA bruner@chem.ufl.edu.
Ding Y; Department of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida Gainesville Florida 32610 USA yding@cop.ufl.edu.

RSC Chem Biol ; 3(4): 436-446, 2022 Apr 06.

Article em En | MEDLINE | ID: mdl-35441146

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article