Retinal Microvasculature-on-a-Chip for Modeling VEGF-Induced Permeability.

Ragelle, Héloïse; Dernick, Karen; Westenskow, Peter D; Kustermann, Stefan

Ragelle, Héloïse; Dernick, Karen; Westenskow, Peter D; Kustermann, Stefan.

Afiliação

Ragelle H; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Dernick K; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Westenskow PD; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.
Kustermann S; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland. stefan.kustermann@roche.com.

Methods Mol Biol ; 2475: 239-257, 2022.

Article em En | MEDLINE | ID: mdl-35451763

Assuntos

Barreira Hematorretiniana; Fator A de Crescimento do Endotélio Vascular; Barreira Hematorretiniana/metabolismo; Permeabilidade Capilar/fisiologia; Humanos; Dispositivos Lab-On-A-Chip; Microvasos/metabolismo; Permeabilidade; Vasos Retinianos/metabolismo; Fator A de Crescimento do Endotélio Vascular/metabolismo

Palavras-chave

3D model; Advanced in vitro model; Blood-retinal barrier; High content imaging; Microvasculature; Organ-on-a-chip; VEGF-induced leakage; Vascular permeability

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematorretiniana / Fator A de Crescimento do Endotélio Vascular Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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