Your browser doesn't support javascript.
loading
Ocular Manifestations of Chikungunya Infection: A Systematic Review.
da Silva, Liziane Cristine Malaquias; da Silva Platner, Fernanda; da Silva Fonseca, Lauany; Rossato, Virgílio Frota; de Andrade, Dian Carlos Pereira; de Sousa Valente, João; Brain, Susan Diana; Fernandes, Elizabeth Soares.
Afiliação
  • da Silva LCM; Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil.
  • da Silva Platner F; Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil.
  • da Silva Fonseca L; Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil.
  • Rossato VF; Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil.
  • de Andrade DCP; Instituto de Pesquisa Pelé Pequeno Príncipe, Av. Silva Jardim No 1632, Curitiba 80240-020, PR, Brazil.
  • de Sousa Valente J; Vascular Biology and Inflammation Section, School of Medicine, King's College London, London SE1 9NH, UK.
  • Brain SD; Vascular Biology and Inflammation Section, School of Medicine, King's College London, London SE1 9NH, UK.
  • Fernandes ES; Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil.
Pathogens ; 11(4)2022 Mar 29.
Article em En | MEDLINE | ID: mdl-35456087
The Chikungunya virus (CHIKV) can cause long lasting symptoms and manifestations. However, there is little information on which ocular ones are most frequent following infection. We performed a systematic review (registered in the International Prospective Register of Systematic Reviews; no CRD42020171928) to establish the most frequent ocular manifestations of CHIKV infection and their associations with gender and age. Articles published until September 2020 were selected from PubMed, Scielo, Cochrane and Scopus databases. Only studies with CHIKV-infected patients and eye alterations were included. Reviews, descriptive studies, or those not investigating the human ocular manifestations of CHIKV, those with patients with other diseases and infections, abstracts and studies without relevant data were excluded. Twenty-five studies were selected for inclusion. Their risk of bias was evaluated by a modified Newcastle-Ottawa scale. The most frequent ocular symptoms of CHIKV infection included ocular pain, inflammation and reduced visual acuity, whilst conjunctivitis and optic neuritis were the most common manifestations of the disease. These occurred mostly in individuals of 42 ± 9.5 years of age and woman. The few available reports on CHIKV-induced eye manifestations highlight the need for further research in the field to gather more substantial evidence linking CHIKV infection, the eye and age/gender. Nonetheless, the data emphasizes that ocular alterations are meaningful occurrences of CHIKV infection which can substantially affect quality of life.
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article