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Retention in care and viral suppression in the PMTCT continuum at a large referral facility in western Kenya.
Humphrey, John M; Songok, Julia; Ofner, Susan; Musick, Beverly; Alera, Marsha; Kipchumba, Bett; McHenry, Megan S; Carlucci, James G; Park, Jun; Mwangi, Winfred; Yiannoutsos, Constantin; Bakoyannis, Giorgos; Wools-Kaloustian, Kara.
Afiliação
  • Humphrey JM; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. humphrjm@iu.edu.
  • Songok J; Department of Paediatrics, Moi University College of Health Sciences, Eldoret, Kenya.
  • Ofner S; Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Musick B; Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Alera M; Academic Model Providing Access to Healthcare, Eldoret, Kenya.
  • Kipchumba B; Department of Reproductive Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
  • McHenry MS; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Carlucci JG; Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Park J; Department of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
  • Mwangi W; Department of Reproductive Health, Moi Teaching and Referral Hospital, Eldoret, Kenya.
  • Yiannoutsos C; Department of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
  • Bakoyannis G; Department of Biostatistics, Richard M. Fairbanks School of Public Health, Indianapolis, IN, USA.
  • Wools-Kaloustian K; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
AIDS Behav ; 26(11): 3494-3505, 2022 Nov.
Article em En | MEDLINE | ID: mdl-35467229
Medical records of pregnant and postpartum women living with HIV and their infants attending a large referral facility in Kenya from 2015 to 2019 were analyzed to identify characteristics associated with retention in care and viral suppression. Women were stratified based on the timing of HIV care enrollment: known HIV-positive (KHP; enrolled pre-pregnancy) and newly HIV-positive (NHP; enrolled during pregnancy). Associations with retention at 18 months postpartum and viral suppression (< 1000 copies/mL) were determined. Among 856 women (20% NHP), retention was 83% for KHPs and 53% for NHPs. Viral suppression was 88% for KHPs and 93% for NHPs, but 19% of women were missing viral load results. In a competing risk model, viral suppression increased by 18% for each additional year of age but was not associated with other factors. Overall, 1.9% of 698 infants with ≥ 1 HIV test result were HIV-positive. Tailored interventions are needed to promote retention and viral load testing, particularly for NHPs, in the PMTCT continuum.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Infecções por HIV / Fármacos Anti-HIV / Retenção nos Cuidados Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Complicações Infecciosas na Gravidez / Infecções por HIV / Fármacos Anti-HIV / Retenção nos Cuidados Idioma: En Ano de publicação: 2022 Tipo de documento: Article