Lower Bladder Toxicity of Salvage Versus Adjuvant Modern Radiotherapy for Prostate Cancer Patients.
In Vivo
; 36(3): 1375-1382, 2022.
Article
em En
| MEDLINE
| ID: mdl-35478143
ABSTRACT
BACKGROUND/AIM:
In prostate cancer, postoperative radiotherapy timing is debated to avoid overtreatments and toxicities. This study compared acute and late rectal and bladder toxicities in the adjuvant and salvage setting. PATIENTS ANDMETHODS:
In total, 129 patients were analyzed in two groups adjuvant radiotherapy (aRT) and salvage radiotherapy (sRT).RESULTS:
In aRT and sRT, grade 1 (G1) acute bladder toxicities were detected in 40 and 30 patients, and grade 2 (G2) in 1 and 6; G1 late bladder toxicities were described in 30 and 20, and G2 in 6 and 2, respectively. In aRT and sRT, acute G1 rectal toxicities were reported in 18 and 27 patients, and G2 in 5 and 4, respectively. Late rectal G1 toxicities were observed in 10 patients, G2 in 6 and G3 in 1 in the aRT. In sRT, 8 patients and 1 developed G1 and G2 toxicities, respectively. Regarding bladder toxicity, a higher incidence occurred in aRT; late toxicity was lower in sRT.CONCLUSION:
Adjuvant and salvage RT in prostate cancer treatment resulted in acceptable toxicities.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prostatectomia
/
Neoplasias da Próstata
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article