IM156, a new AMPK activator, protects against polymicrobial sepsis.

Kang, Ji Hyeon; Lee, Sung Kyun; Yun, Nam Joo; Kim, Ye Seon; Song, Jason Jungsik; Bae, Yoe-Sik

Kang, Ji Hyeon; Lee, Sung Kyun; Yun, Nam Joo; Kim, Ye Seon; Song, Jason Jungsik; Bae, Yoe-Sik.

Afiliação

Kang JH; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Lee SK; Center for Convergent Research of Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea.
Yun NJ; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Kim YS; Department of Biological Sciences, Sungkyunkwan University, Suwon, Republic of Korea.
Song JJ; Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Bae YS; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea.

J Cell Mol Med ; 26(12): 3378-3386, 2022 06.

Article em En | MEDLINE | ID: mdl-35502484

Assuntos

Armadilhas Extracelulares; Sepse; Proteínas Quinases Ativadas por AMP/metabolismo; Animais; Citocinas/metabolismo; Modelos Animais de Doenças; Armadilhas Extracelulares/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Neutrófilos/metabolismo; Sepse/metabolismo

Palavras-chave

AMP-activated protein kinase; IM156; caecal ligation and puncture; neutrophil extracellular traps; sepsis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Armadilhas Extracelulares Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sepse / Armadilhas Extracelulares Idioma: En Ano de publicação: 2022 Tipo de documento: Article