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Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives.
Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano.
Afiliação
  • Bononi G; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Di Stefano M; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Poli G; Department of Life Sciences, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy.
  • Ortore G; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Meier P; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Masetto F; Institute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, CH-3012 Bern, Switzerland.
  • Caligiuri I; Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, DeBoelelaan 1117, 1081HV Amsterdam, The Netherlands.
  • Rizzolio F; Pathology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.
  • Macchia M; Pathology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, 33081 Aviano, Italy.
  • Chicca A; Department of Molecular Sciences and Nanosystems, Ca' Foscari University, 30123 Venezia, Italy.
  • Avan A; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
  • Giovannetti E; Institute of Biochemistry and Molecular Medicine, NCCR TransCure, University of Bern, CH-3012 Bern, Switzerland.
  • Vagaggini C; Metabolic Syndrome Research Center, Mashhad University of Medical Science, Mashhad 91886-17871, Iran.
  • Brai A; Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, DeBoelelaan 1117, 1081HV Amsterdam, The Netherlands.
  • Dreassi E; Cancer Pharmacology Lab, Fondazione Pisana per la Scienza, via Giovannini 13, 56017 San Giuliano Terme, Pisa, Italy.
  • Valoti M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy.
  • Minutolo F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy.
  • Granchi C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy.
  • Gertsch J; Department of Life Sciences, University of Siena, Via Aldo Moro, 2, 53100 Siena, Italy.
  • Tuccinardi T; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.
J Med Chem ; 65(10): 7118-7140, 2022 05 26.
Article em En | MEDLINE | ID: mdl-35522977
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Monoacilglicerol Lipases Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Monoacilglicerol Lipases Idioma: En Ano de publicação: 2022 Tipo de documento: Article