Andrographolide, isolated from <i>Andrographis paniculata</i><i>,</i> induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production.

Doi, Hiroki; Matsui, Taei; Dijkstra, Johannes M; Ogasawara, Atsushi; Higashimoto, Yuki; Imamura, Seiji; Ohye, Tamae; Takematsu, Hiromu; Katsuda, Itsuro; Akiyama, Hidehiko

Andrographolide, isolated from Andrographis paniculata, induces apoptosis in monocytic leukemia and multiple myeloma cells via augmentation of reactive oxygen species production.

Doi, Hiroki; Matsui, Taei; Dijkstra, Johannes M; Ogasawara, Atsushi; Higashimoto, Yuki; Imamura, Seiji; Ohye, Tamae; Takematsu, Hiromu; Katsuda, Itsuro; Akiyama, Hidehiko.

Afiliação

Doi H; Field of Clinical Laboratory Sciences, Fujita Health University Graduate School of Health Sciences, Toyoake, 470-1192, Japan.
Matsui T; Field of Clinical Laboratory Sciences, Fujita Health University Graduate School of Health Sciences, Toyoake, 470-1192, Japan.
Dijkstra JM; Faculty of Medical Technology, Fujita Health University School of Medical Sciences, Toyoake, 470-1192, Japan.
Ogasawara A; Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, 470-1192, Japan.
Higashimoto Y; Field of Clinical Laboratory Sciences, Fujita Health University Graduate School of Health Sciences, Toyoake, 470-1192, Japan.
Imamura S; Faculty of Medical Technology, Fujita Health University School of Medical Sciences, Toyoake, 470-1192, Japan.
Ohye T; Faculty of Medical Technology, Fujita Health University School of Medical Sciences, Toyoake, 470-1192, Japan.
Takematsu H; Faculty of Medical Technology, Fujita Health University School of Medical Sciences, Toyoake, 470-1192, Japan.
Katsuda I; Field of Clinical Laboratory Sciences, Fujita Health University Graduate School of Health Sciences, Toyoake, 470-1192, Japan.
Akiyama H; Faculty of Medical Technology, Fujita Health University School of Medical Sciences, Toyoake, 470-1192, Japan.

F1000Res ; 10: 542, 2021.

Article em En | MEDLINE | ID: mdl-35528957

Assuntos

Diterpenos; Neoplasias Hematológicas; Leucemia; Mieloma Múltiplo; Andrographis paniculata; Apoptose; Linhagem Celular Tumoral; Citarabina/farmacologia; Diterpenos/farmacologia; Humanos; Mieloma Múltiplo/tratamento farmacológico; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Andrographis paniculata; andrographolide; apoptosis; monocytic leukemia cells; multiple myeloma cells; reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Neoplasias Hematológicas / Diterpenos / Mieloma Múltiplo Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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