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Molecular basis for inhibiting human glucose transporters by exofacial inhibitors.
Wang, Nan; Zhang, Shuo; Yuan, Yafei; Xu, Hanwen; Defossa, Elisabeth; Matter, Hans; Besenius, Melissa; Derdau, Volker; Dreyer, Matthias; Halland, Nis; He, Kaihui Hu; Petry, Stefan; Podeschwa, Michael; Tennagels, Norbert; Jiang, Xin; Yan, Nieng.
Afiliação
  • Wang N; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
  • Zhang S; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
  • Yuan Y; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
  • Xu H; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
  • Defossa E; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Matter H; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Besenius M; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Derdau V; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Dreyer M; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Halland N; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • He KH; Sanofi-Aventis Deutschland GmbH, R&D, CMC Synthetics Early Development Analytics, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Petry S; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Podeschwa M; Sanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, 65926, Frankfurt am Main, Germany.
  • Tennagels N; Bayer AG, R&D, Pharmaceuticals, TA Endocrinology, Metabolism & Reproductive Health, DIU Exploratory Pathobiology, 42096, Wuppertal, Germany.
  • Jiang X; State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. xin.jiang@unsw.edu.au.
  • Yan N; School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, 2052, Australia. xin.jiang@unsw.edu.au.
Nat Commun ; 13(1): 2632, 2022 05 12.
Article em En | MEDLINE | ID: mdl-35552392
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Facilitadoras de Transporte de Glucose / Insulina Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Facilitadoras de Transporte de Glucose / Insulina Idioma: En Ano de publicação: 2022 Tipo de documento: Article