Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.

Pei, Zijie; Ning, Jie; Zhang, Ning; Zhang, Xu; Zhang, Helin; Zhang, Rong

Pei, Zijie; Ning, Jie; Zhang, Ning; Zhang, Xu; Zhang, Helin; Zhang, Rong.

Afiliação

Pei Z; Department of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Ning J; Department of Toxicology, Hebei Medical University, Shijiazhuang 050017, China.
Zhang N; Department of Toxicology, Hebei Medical University, Shijiazhuang 050017, China.
Zhang X; Department of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Zhang H; Department of Thoracic Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China. Electronic address: zhl_dr@163.com.
Zhang R; Department of Toxicology, Hebei Medical University, Shijiazhuang 050017, China; Hebei Key Laboratory of Environment and Human Health, Hebei Medical University, Shijiazhuang 050017, China. Electronic address: rongzhang@hebmu.edu.cn.

NanoImpact ; 26: 100400, 2022 04.

Article em En | MEDLINE | ID: mdl-35560285

Assuntos

Nanopartículas; Fuligem; Animais; Carcinógenos/farmacologia; Proteínas de Ciclo Celular; Pulmão; Nanopartículas/toxicidade; Proteínas Serina-Treonina Quinases; Proteínas Proto-Oncogênicas; Ratos; Fuligem/toxicidade; Quinase 1 Polo-Like

Palavras-chave

Carbon black nanoparticles (CBNPs); DNA damage; Genomic instability; PLK1; Pulmonary toxicity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fuligem / Nanopartículas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fuligem / Nanopartículas Idioma: En Ano de publicação: 2022 Tipo de documento: Article