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C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons.
Marchi, Paolo M; Marrone, Lara; Brasseur, Laurent; Coens, Audrey; Webster, Christopher P; Bousset, Luc; Destro, Marco; Smith, Emma F; Walther, Christa G; Alfred, Victor; Marroccella, Raffaele; Graves, Emily J; Robinson, Darren; Shaw, Allan C; Wan, Lai Mei; Grierson, Andrew J; Ebbens, Stephen J; De Vos, Kurt J; Hautbergue, Guillaume M; Ferraiuolo, Laura; Melki, Ronald; Azzouz, Mimoun.
Afiliação
  • Marchi PM; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Marrone L; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Brasseur L; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Coens A; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Webster CP; The French Alternative Energies and Atomic Energy Commission (CEA), Institut François Jacob (MIRcen) and The French National Centre for Scientific Research (CNRS), Laboratory of Neurodegenerative Diseases (UMR9199), Fontenay-aux-Roses, France.
  • Bousset L; The French Alternative Energies and Atomic Energy Commission (CEA), Institut François Jacob (MIRcen) and The French National Centre for Scientific Research (CNRS), Laboratory of Neurodegenerative Diseases (UMR9199), Fontenay-aux-Roses, France.
  • Destro M; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Smith EF; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Walther CG; The French Alternative Energies and Atomic Energy Commission (CEA), Institut François Jacob (MIRcen) and The French National Centre for Scientific Research (CNRS), Laboratory of Neurodegenerative Diseases (UMR9199), Fontenay-aux-Roses, France.
  • Alfred V; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Marroccella R; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Graves EJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Robinson D; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Shaw AC; Centre for Membrane Interactions and Dynamics, University of Sheffield, Western Bank, Sheffield, UK.
  • Wan LM; The Wolfson Light Microscopy Facility, University of Sheffield, Sheffield, UK.
  • Grierson AJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Ebbens SJ; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • De Vos KJ; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Hautbergue GM; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Ferraiuolo L; Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK.
  • Melki R; Neuroscience Institute, University of Sheffield, Western Bank, Sheffield, UK.
  • Azzouz M; The Wolfson Light Microscopy Facility, University of Sheffield, Sheffield, UK.
Life Sci Alliance ; 5(9)2022 09.
Article em En | MEDLINE | ID: mdl-35568435
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article