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Intestinal microbiota-mediated biotransformations alter the pharmacokinetics of the major metabolites of azathioprine in rats after oral administration.
Wang, Shanshan; Qin, Yan; Wen, Qiuyu; Xia, Quan; Gu, Ruoyu; Wang, Sheng; Chen, GuanJun; Tan, Chao; Shen, Chenlin; Song, Shuai.
Afiliação
  • Wang S; Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, PR China.
  • Qin Y; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui Medical University, Hefei, 230032, PR China.
  • Wen Q; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui Medical University, Hefei, 230032, PR China; Department of Pharmacy, The First Affiliated Hospital of Anhui
  • Xia Q; Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, PR China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui
  • Gu R; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui Medical University, Hefei, 230032, PR China.
  • Wang S; Center for Scientific Research of Anhui Medical University, Hefei, 230032, PR China.
  • Chen G; Center for Scientific Research of Anhui Medical University, Hefei, 230032, PR China.
  • Tan C; Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, PR China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui
  • Shen C; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui Medical University, Hefei, 230032, PR China; Hefei Kaifan Analytical Technology Co., Ltd., Hefei, 230051, P
  • Song S; Department of Pharmacy, The First Affiliated Hospital of Anhui Medical University, Hefei, 230032, PR China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, Institute for Liver Diseases of Anhui Medical University, School of Pharmacy, Anhui
Drug Metab Pharmacokinet ; 45: 100458, 2022 Aug.
Article em En | MEDLINE | ID: mdl-35569194

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azatioprina / Microbioma Gastrointestinal Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azatioprina / Microbioma Gastrointestinal Idioma: En Ano de publicação: 2022 Tipo de documento: Article