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Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Loveland, Anna B; Svidritskiy, Egor; Susorov, Denis; Lee, Soojin; Park, Alexander; Zvornicanin, Sarah; Demo, Gabriel; Gao, Fen-Biao; Korostelev, Andrei A.
Afiliação
  • Loveland AB; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Svidritskiy E; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Susorov D; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Lee S; Department of Neurology, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Park A; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Zvornicanin S; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Demo G; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA.
  • Gao FB; Central European Institute of Technology, Masaryk University, Kamenice 5, Brno, 625 00, Czech Republic.
  • Korostelev AA; Department of Neurology, UMass Chan Medical School, 368 Plantation Street, Worcester, MA, 01605, USA. Fen-Biao.Gao@umassmed.edu.
Nat Commun ; 13(1): 2776, 2022 05 19.
Article em En | MEDLINE | ID: mdl-35589706
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Demência Frontotemporal / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2022 Tipo de documento: Article