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Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies.
Das, Jishnu; Fallon, Jonathan K; Yu, Timothy C; Michell, Ashlin; Suscovich, Todd J; Linde, Caitlyn; Natarajan, Harini; Weiner, Joshua; Coccia, Margherita; Gregory, Scott; Ackerman, Margaret E; Bergmann-Leitner, Elke; Fontana, Laura; Dutta, Sheetij; Lauffenburger, Douglas A; Jongert, Erik; Wille-Reece, Ulrike; Alter, Galit.
Afiliação
  • Das J; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Fallon JK; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Yu TC; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Michell A; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Suscovich TJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Linde C; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Natarajan H; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.
  • Weiner J; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.
  • Coccia M; GSK Vaccines, Rixensart, Belgium.
  • Gregory S; PATH's Malaria Vaccine Initiative, Washington, DC, USA.
  • Ackerman ME; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.
  • Bergmann-Leitner E; Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Fontana L; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA.
  • Dutta S; Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Lauffenburger DA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Jongert E; GSK Vaccines, Rixensart, Belgium.
  • Wille-Reece U; PATH's Malaria Vaccine Initiative, Washington, DC, USA.
  • Alter G; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA. Electronic address: galter@mgh.harvard.edu.
Med ; 2(11): 1269-1286.e9, 2021 11 12.
Article em En | MEDLINE | ID: mdl-35590199
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Antimaláricas / Malária Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vacinas Antimaláricas / Malária Idioma: En Ano de publicação: 2021 Tipo de documento: Article