UPF1 adds an m6A feather to its (de)cap.
Cell Rep
; 39(8): 110898, 2022 05 24.
Article
em En
| MEDLINE
| ID: mdl-35613576
ABSTRACT
The N6-methyladenosine modification (m6A) modulates eukaryotic mRNA decay. In this issue of Cell Reports, Boo et al. describe a mechanism for degradation of m6A-containing mRNAs by 5'-decapping, which occurs through the recruitment of the degradation factor UPF1 via the m6A reader protein YTHDF2.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Adenosina
/
Proteínas de Ligação a RNA
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article