Photo-PISA: Shedding Light on Polymerization-Induced Self-Assembly.
ACS Macro Lett
; 4(11): 1249-1253, 2015 Nov 17.
Article
em En
| MEDLINE
| ID: mdl-35614822
ABSTRACT
Herein we report an aqueous photoinitiated polymerization-induced self-assembly (photo-PISA) for the preparation of a remarkably diverse set of complex polymer nanoparticle morphologies (e.g., spheres, worms, and vesicles) at room temperature. Ultrafast polymerization rates were achieved, with near quantitative monomer conversion within 15 min of visible light irradiation. An important feature of the photo-PISA is that diblock copolymer vesicles can be prepared under mild conditions (room temperature, aqueous medium, visible light), which will be important for the preparation of functional vesicles loaded with biorelated species (e.g., proteins). As a proof of concept, silica nanoparticles and bovine serum albumin (BSA) were encapsulated in situ within vesicles via the photo-PISA process.
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MEDLINE
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En
Ano de publicação:
2015
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Article