MicroRNA-7a-5p ameliorates diabetic peripheral neuropathy by regulating VDAC1/JNK/c-JUN pathway.

Jiao, Yang; Zhang, Yue-Hua; Wang, Chun-Yan; Yu, Yang; Li, Yi-Ze; Cui, Wei; Li, Qing; Yu, Yong-Hao

Jiao, Yang; Zhang, Yue-Hua; Wang, Chun-Yan; Yu, Yang; Li, Yi-Ze; Cui, Wei; Li, Qing; Yu, Yong-Hao.

Afiliação

Jiao Y; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Zhang YH; Tianjin Research Institute of Anesthesiology, Tianjin, China.
Wang CY; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Yu Y; Tianjin Research Institute of Anesthesiology, Tianjin, China.
Li YZ; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Cui W; Tianjin Research Institute of Anesthesiology, Tianjin, China.
Li Q; Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin, China.
Yu YH; Tianjin Research Institute of Anesthesiology, Tianjin, China.

Diabet Med ; 40(1): e14890, 2023 01.

Article em En | MEDLINE | ID: mdl-35616949

Assuntos

Diabetes Mellitus Experimental; Neuropatias Diabéticas; MicroRNAs; Animais; Ratos; Apoptose; Cálcio/efeitos adversos; Cálcio/metabolismo; Neuropatias Diabéticas/genética; Neuropatias Diabéticas/patologia; MicroRNAs/genética; MicroRNAs/metabolismo; Estreptozocina; Canal de Ânion 1 Dependente de Voltagem

Palavras-chave

JNK/c-JUN pathway; MiR-7a-5p; RSC96 cells; VDAC1; diabetic peripheral neuropathy; mitochondrial dysfunction

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: MicroRNAs / Diabetes Mellitus Experimental / Neuropatias Diabéticas Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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