Topical Simvastatin Improves Lesions of Diffuse Normolipemic Plane Xanthoma by Inhibiting Foam Cell Pyroptosis.

Zha, Siyuan; Yu, Xia; Wang, Xiaoxiao; Gu, Yan; Tan, Yidong; Lu, Ying; Yao, Zhirong

Zha, Siyuan; Yu, Xia; Wang, Xiaoxiao; Gu, Yan; Tan, Yidong; Lu, Ying; Yao, Zhirong.

Afiliação

Zha S; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yu X; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang X; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Gu Y; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tan Y; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Lu Y; Institute of Dermatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yao Z; Department of Dermatology, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Front Immunol ; 13: 865704, 2022.

Article em En | MEDLINE | ID: mdl-35619689

Assuntos

Células Espumosas; Xantomatose; Criança; Células Espumosas/metabolismo; Humanos; Inflamação/metabolismo; Proteína 3 que Contém Domínio de Pirina da Família NLR/metabolismo; Pomadas/metabolismo; Piroptose; Sinvastatina/farmacologia; Xantomatose/tratamento farmacológico; Xantomatose/metabolismo

Palavras-chave

diffuse plane xanthoma; foam cells; oxidized-LDL; pyroptosis; simvastatin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantomatose / Células Espumosas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Xantomatose / Células Espumosas Idioma: En Ano de publicação: 2022 Tipo de documento: Article