CSMD1 suppresses cancer progression by inhibiting proliferation, epithelial-mesenchymal transition, chemotherapy-resistance and inducing immunosuppression in esophageal squamous cell carcinoma.

Wang, Xing; Chen, Xinwei; Liu, Yuanyuan; Huang, Shan; Ding, Jian; Wang, Baoxin; Dong, Pin; Sun, Zhenfeng; Chen, Lixiao

Wang, Xing; Chen, Xinwei; Liu, Yuanyuan; Huang, Shan; Ding, Jian; Wang, Baoxin; Dong, Pin; Sun, Zhenfeng; Chen, Lixiao.

Afiliação

Wang X; Translational Medicine Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, 201620, Shanghai, China.
Chen X; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Liu Y; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Huang S; National Engineering Research Center for Nanomedicine, Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Tongji Hospital, Huazhong University of Science and Technology, 430074, Wuhan, China.
Ding J; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Wang B; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Dong P; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Sun Z; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. Electronic address: zhenfeng.sun@shgh.cn.
Chen L; Department of Otolaryngology: Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China. Electronic address: lixiao.chen@shgh.cn.

Exp Cell Res ; 417(2): 113220, 2022 08 15.

Article em En | MEDLINE | ID: mdl-35623420

Assuntos

Carcinoma de Células Escamosas; Neoplasias Esofágicas; Carcinoma de Células Escamosas do Esôfago; Animais; Linfócitos T CD8-Positivos/patologia; Carcinoma de Células Escamosas/tratamento farmacológico; Carcinoma de Células Escamosas/genética; Carcinoma de Células Escamosas/metabolismo; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células; Citocinas/metabolismo; Transição Epitelial-Mesenquimal/genética; Neoplasias Esofágicas/tratamento farmacológico; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/metabolismo; Carcinoma de Células Escamosas do Esôfago/tratamento farmacológico; Carcinoma de Células Escamosas do Esôfago/genética; Carcinoma de Células Escamosas do Esôfago/metabolismo; Regulação Neoplásica da Expressão Gênica; Humanos; Terapia de Imunossupressão; Proteínas de Membrana/metabolismo; Camundongos; Proteínas Supressoras de Tumor/metabolismo

Palavras-chave

CSMD1; Chemotherapy resistance; Esophageal squamous cell carcinoma; Immunotherapy; Tumor suppressor gene

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Carcinoma de Células Escamosas do Esôfago Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google