HMGN3 represses transcription of epithelial regulators to promote migration of cholangiocarcinoma in a SNAI2-dependent manner.

Sorin, Supannika; Kubota, Sho; Hamidi, Sofiane; Yokomizo-Nakano, Takako; Vaeteewoottacharn, Kulthida; Wongkham, Sopit; Waraasawapati, Sakda; Pairojkul, Chawalit; Bai, Jie; Morii, Mariko; Sheng, Guojun; Sawanyawisuth, Kanlayanee; Sashida, Goro

Sorin, Supannika; Kubota, Sho; Hamidi, Sofiane; Yokomizo-Nakano, Takako; Vaeteewoottacharn, Kulthida; Wongkham, Sopit; Waraasawapati, Sakda; Pairojkul, Chawalit; Bai, Jie; Morii, Mariko; Sheng, Guojun; Sawanyawisuth, Kanlayanee; Sashida, Goro.

Afiliação

Sorin S; Department of Biochemistry, Faculty of Medicine, Center for Translational Medicine, Khon Kaen University, Khon Kaen, Thailand.
Kubota S; Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand.
Hamidi S; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Yokomizo-Nakano T; Laboratory of Developmental Morphogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Vaeteewoottacharn K; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Wongkham S; Department of Biochemistry, Faculty of Medicine, Center for Translational Medicine, Khon Kaen University, Khon Kaen, Thailand.
Waraasawapati S; Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand.
Pairojkul C; Department of Biochemistry, Faculty of Medicine, Center for Translational Medicine, Khon Kaen University, Khon Kaen, Thailand.
Bai J; Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Morii M; Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Sheng G; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Sawanyawisuth K; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.
Sashida G; Laboratory of Developmental Morphogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, Kumamoto, Japan.

FASEB J ; 36(7): e22345, 2022 07.

Article em En | MEDLINE | ID: mdl-35635715

Assuntos

Neoplasias dos Ductos Biliares; Colangiocarcinoma; Neoplasias dos Ductos Biliares/genética; Neoplasias dos Ductos Biliares/patologia; Ductos Biliares Intra-Hepáticos/metabolismo; Ductos Biliares Intra-Hepáticos/patologia; Colangiocarcinoma/genética; Colangiocarcinoma/patologia; Regulação da Expressão Gênica; Proteínas HMGN/genética; Proteínas HMGN/metabolismo; Humanos; Fatores de Transcrição da Família Snail/genética; Fatores de Transcrição da Família Snail/metabolismo; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo

Palavras-chave

HMGN; epithelial mesenchymal transition; histone deacetylase; liver fluke; transcription factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias dos Ductos Biliares / Colangiocarcinoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article