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STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer.
Wang, Qiwei; Bergholz, Johann S; Ding, Liya; Lin, Ziying; Kabraji, Sheheryar K; Hughes, Melissa E; He, Xiadi; Xie, Shaozhen; Jiang, Tao; Wang, Weihua; Zoeller, Jason J; Kim, Hye-Jung; Roberts, Thomas M; Konstantinopoulos, Panagiotis A; Matulonis, Ursula A; Dillon, Deborah A; Winer, Eric P; Lin, Nancy U; Zhao, Jean J.
Afiliação
  • Wang Q; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bergholz JS; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Ding L; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Lin Z; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Kabraji SK; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Hughes ME; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • He X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Xie S; Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Jiang T; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Wang W; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Zoeller JJ; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Kim HJ; Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Roberts TM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Konstantinopoulos PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Matulonis UA; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Dillon DA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Winer EP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lin NU; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.
Nat Commun ; 13(1): 3022, 2022 05 31.
Article em En | MEDLINE | ID: mdl-35641483
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Inibidores de Poli(ADP-Ribose) Polimerases Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Inibidores de Poli(ADP-Ribose) Polimerases Idioma: En Ano de publicação: 2022 Tipo de documento: Article