Ginsenoside Rg1 suppresses paraquat-induced epithelial cell senescence by enhancing autophagy in an ATG12-dependent manner.

Huang, Changbao; Xue, Xiang; Gong, Nengkai; Jiang, Jinghan

Huang, Changbao; Xue, Xiang; Gong, Nengkai; Jiang, Jinghan.

Afiliação

Huang C; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, Anhui, PR China.
Xue X; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, Anhui, PR China.
Gong N; Department of Emergency Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, Anhui, PR China.
Jiang J; Department of General Practice Medicine, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, Anhui, PR China.

Environ Toxicol ; 37(9): 2302-2313, 2022 Sep.

Article em En | MEDLINE | ID: mdl-35657166

Assuntos

Proteína 12 Relacionada à Autofagia; Ginsenosídeos; Paraquat; Fibrose Pulmonar; Animais; Autofagia; Proteína 12 Relacionada à Autofagia/metabolismo; Senescência Celular; Células Epiteliais/efeitos dos fármacos; Ginsenosídeos/farmacologia; Camundongos; Paraquat/toxicidade; Fibrose Pulmonar/metabolismo

Palavras-chave

autophagy; ginsenoside Rg1; paraquat; pulmonary fibrosis; senescence-associated secretory phenotype

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paraquat / Fibrose Pulmonar / Ginsenosídeos / Proteína 12 Relacionada à Autofagia Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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