Ent-abietane diterpenoid lactone glycosides and a phenolic glycoside from Phlogacanthus pulcherrimus T. Anderson with cytotoxic and cancer chemopreventive activities.

Kheawchaum, Surasak; Mahidol, Chulabhorn; Thongnest, Sanit; Boonsombat, Jutatip; Batsomboon, Paratchata; Sitthimonchai, Somkid; Ruchirawat, Somsak; Prawat, Hunsa

Kheawchaum, Surasak; Mahidol, Chulabhorn; Thongnest, Sanit; Boonsombat, Jutatip; Batsomboon, Paratchata; Sitthimonchai, Somkid; Ruchirawat, Somsak; Prawat, Hunsa.

Afiliação

Kheawchaum S; Laboratory of Natural Products, Chulabhorn Research Institute, Bangkok, 10210, Thailand.
Mahidol C; Laboratory of Natural Products, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, 10210, Thailand.
Thongnest S; Laboratory of Natural Products, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, MHESI, Thailand.
Boonsombat J; Laboratory of Natural Products, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, MHESI, Thailand.
Batsomboon P; Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, Bangkok, 10210, Thailand.
Sitthimonchai S; Laboratory of Chemical Carcinogenesis, Chulabhorn Research Institute, Bangkok, 10210, Thailand.
Ruchirawat S; Laboratory of Medicinal Chemistry, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Program in Chemical Sciences, Chulabhorn Graduate Institute, Chulabhorn Royal Academy, Bangkok, 10210, Thailand; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, MHESI, Thailand.
Prawat H; Laboratory of Natural Products, Chulabhorn Research Institute, Bangkok, 10210, Thailand; Center of Excellence on Environmental Health and Toxicology (EHT), OPS, MHESI, Thailand. Electronic address: hunsa@cri.or.th.

Phytochemistry ; 201: 113261, 2022 Sep.

Article em En | MEDLINE | ID: mdl-35662549

Assuntos

Acanthaceae; Neoplasias; Abietanos/química; Abietanos/farmacologia; Glicosídeos/farmacologia; Células HeLa; Humanos; Lactonas/química; Estrutura Molecular

Palavras-chave

Acanthaceae; Antioxidant activity; Aromatase inhibition; Chemoprevention; Cytotoxicity; Diterpenoid lactones; Ent-abietanes; Phlogacanthus pulcherrimus; Phlogoside A; Pulcherrimosides AI

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acanthaceae / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acanthaceae / Neoplasias Idioma: En Ano de publicação: 2022 Tipo de documento: Article