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Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension.
Chelladurai, Prakash; Kuenne, Carsten; Bourgeois, Alice; Günther, Stefan; Valasarajan, Chanil; Cherian, Anoop V; Rottier, Robbert J; Romanet, Charlotte; Weigert, Andreas; Boucherat, Olivier; Eichstaedt, Christina A; Ruppert, Clemens; Guenther, Andreas; Braun, Thomas; Looso, Mario; Savai, Rajkumar; Seeger, Werner; Bauer, Uta-Maria; Bonnet, Sébastien; Pullamsetti, Soni Savai.
Afiliação
  • Chelladurai P; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Kuenne C; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Bourgeois A; Department of Medicine Laval University, Pulmonary Hypertension and Vascular Biology Research Group of Quebec Heart and Lung Institute, G1V 4G5 Quebec, Canada.
  • Günther S; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Valasarajan C; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Cherian AV; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Rottier RJ; Department of Pediatric Surgery, Erasmus Medical Center-Sophia Children's Hospital, Wytemaweg 80, 3015CN Rotterdam, Netherlands.
  • Romanet C; Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands.
  • Weigert A; Department of Medicine Laval University, Pulmonary Hypertension and Vascular Biology Research Group of Quebec Heart and Lung Institute, G1V 4G5 Quebec, Canada.
  • Boucherat O; Institute of Biochemistry I, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
  • Eichstaedt CA; Department of Medicine Laval University, Pulmonary Hypertension and Vascular Biology Research Group of Quebec Heart and Lung Institute, G1V 4G5 Quebec, Canada.
  • Ruppert C; Centre for Pulmonary Hypertension, Thoraxklinik Heidelberg GmbH, Translational Lung Research Center Heidelberg (TLRC), Member of the German Center for Lung Research (DZL), Laboratory for Molecular Diagnostics, Institute of Human Genetics, Heidelberg University, 69126 Heidelberg, Germany.
  • Guenther A; Department of Internal Medicine, Member of the DZL, Member of CPI, Justus Liebig University, Giessen 35392, Germany.
  • Braun T; Department of Internal Medicine, Member of the DZL, Member of CPI, Justus Liebig University, Giessen 35392, Germany.
  • Looso M; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Savai R; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Seeger W; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
  • Bauer UM; Department of Internal Medicine, Member of the DZL, Member of CPI, Justus Liebig University, Giessen 35392, Germany.
  • Bonnet S; Institute for Lung Health (ILH), Member of the DZL, Justus Liebig University, Giessen 35392, Germany.
  • Pullamsetti SS; Max Planck Institute for Heart and Lung Research, Member of the German Center for Lung Research (DZL), Member of the Cardio-Pulmonary Institute (CPI), 61231 Bad Nauheim, Germany.
Sci Transl Med ; 14(648): eabe5407, 2022 06 08.
Article em En | MEDLINE | ID: mdl-35675437
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão Pulmonar Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hipertensão Pulmonar Idioma: En Ano de publicação: 2022 Tipo de documento: Article