Perinatal outcomes of pregnancies with twin-anemia polycythemia sequence complicating twin-to-twin transfusion syndrome using different twin-anemia polycythemia sequence diagnostic criteria.
Prenat Diagn
; 42(8): 985-993, 2022 07.
Article
em En
| MEDLINE
| ID: mdl-35686505
ABSTRACT
OBJECTIVE:
To investigate whether the presence of twin-anemia polycythemia sequence (TAPS) with twin-to-twin transfusion syndrome (TTTS) or post-laser TAPS would change outcomes using different TAPS diagnostic criteria.METHODS:
TTTS cases undergoing laser surgery between 2012 and 2020 were included. Groups included pre-laser TTTS-only compared to TTTS + TAPS, and no post-laser TAPS compared to post-laser TAPS. Three prenatal TAPS diagnostic criteria were used group A middle cerebral artery-peak systolic velocity (MCA-PSV) > 1.5 MoM in one twin and <1 MoM in the other twin, group B inter-twin MCA-PSV difference >1 MoM, and group C inter-twin MCA-PSV difference >0.5 MoM. Perinatal outcomes including survival and severe cerebral injury were investigated.RESULTS:
174 laser procedures were included. TTTS + TAPS cases were 16 in group A, 17 in group B, and 29 in group C. Post-laser TAPS cases were 11 in group A, 6 in group B, and 12 in group C. There were no differences in preoperative, operative variables and outcomes including survival and severe cerebral injury between groups using all three TAPS diagnostic criteria. The incidence of TTTS + TAPS was highest in group C (16.7%), then group B (9.8%), followed by group A (9.2%). The incidence of post-laser TAPS was highest in group C (9%), then group A (8.3%), followed by group B (4.5%).CONCLUSION:
Presence of TAPS complicating TTTS and presence of post-laser TAPS do not seem to be associated with worse perinatal outcomes including postnatal-ultrasound detected cerebral injury using three different TAPS criteria. Collaborative studies are needed to investigate the validity and the performance of different TAPS criteria.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Policitemia
/
Transfusão Feto-Fetal
/
Anemia
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article