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Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential.
Dejmek, Milan; Sála, Michal; Brazdova, Andrea; Vanekova, Lenka; Smola, Miroslav; Klíma, Martin; Brehová, Petra; Budesínský, Milos; Dracínský, Martin; Procházková, Eliska; Zavrel, Martin; Simák, Ondrej; Páv, Ondrej; Boura, Evzen; Birkus, Gabriel; Nencka, Radim.
Afiliação
  • Dejmek M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Sála M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Brazdova A; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Vanekova L; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic; Faculty of Science, Charles University, 128 00 Prague, Czech Republic.
  • Smola M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Klíma M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Brehová P; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Budesínský M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Dracínský M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Procházková E; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Zavrel M; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Simák O; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Páv O; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Boura E; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Birkus G; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
  • Nencka R; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic. Electronic address: nencka@uochb.cas.cz.
Structure ; 30(8): 1146-1156.e11, 2022 08 04.
Article em En | MEDLINE | ID: mdl-35690061
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Nucleotídeos Cíclicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Nucleotídeos Cíclicos Idioma: En Ano de publicação: 2022 Tipo de documento: Article