Photocatalytic 1,2-oxo-alkylation reaction of styrenes with diazoacetates.
Chem Commun (Camb)
; 58(54): 7526-7529, 2022 Jul 05.
Article
em En
| MEDLINE
| ID: mdl-35703319
ABSTRACT
We report on the photocatalytic 1,2-difunctionalization reaction of styrenes with acceptor-only diazoalkanes. In the presence of DABCO and tBuOOH, the carbene reactivity of diazoalkanes can be suppressed and a 1,2 oxo-alkylation reaction can be achieved (32 examples, up to 94% yield) without the formation of cyclopropane by-products via the formation of radical intermediates from ethyl diazoacetate.
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MEDLINE
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En
Ano de publicação:
2022
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Article