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Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells.
Saghaleyni, Rasool; Malm, Magdalena; Moruzzi, Noah; Zrimec, Jan; Razavi, Ronia; Wistbacka, Num; Thorell, Hannes; Pintar, Anton; Hober, Andreas; Edfors, Fredrik; Chotteau, Veronique; Berggren, Per-Olof; Grassi, Luigi; Zelezniak, Aleksej; Svensson, Thomas; Hatton, Diane; Nielsen, Jens; Robinson, Jonathan L; Rockberg, Johan.
Afiliação
  • Saghaleyni R; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
  • Malm M; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden.
  • Moruzzi N; The Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institute, 17176 Stockholm, Sweden.
  • Zrimec J; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
  • Razavi R; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden.
  • Wistbacka N; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden.
  • Thorell H; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden.
  • Pintar A; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden.
  • Hober A; Science for Life Laboratory, KTH - Royal Institute of Technology, 171 65 Solna, Sweden.
  • Edfors F; Science for Life Laboratory, KTH - Royal Institute of Technology, 171 65 Solna, Sweden.
  • Chotteau V; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Industrial Biotechnology, 106 91 Stockholm, Sweden.
  • Berggren PO; The Rolf Luft Research Center for Diabetes and Endocrinology, Department of Molecular Medicine and Surgery, Karolinska Institute, 17176 Stockholm, Sweden.
  • Grassi L; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Zelezniak A; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden.
  • Svensson T; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden; Department of Biology and Biological Engineering, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Chalmers University of Technology, Kemivägen 10, 41258 Gothenb
  • Hatton D; Cell Culture & Fermentation Sciences, BioPharmaceutical Development, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Nielsen J; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.
  • Robinson JL; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden; Department of Biology and Biological Engineering, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Chalmers University of Technology, Kemivägen 10, 41258 Gothenb
  • Rockberg J; KTH - Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology, and Health, Department of Protein Science, 106 91 Stockholm, Sweden. Electronic address: johan.rockberg@biotech.kth.se.
Cell Rep ; 39(11): 110936, 2022 06 14.
Article em En | MEDLINE | ID: mdl-35705050
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eritropoetina / Estresse do Retículo Endoplasmático Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Eritropoetina / Estresse do Retículo Endoplasmático Idioma: En Ano de publicação: 2022 Tipo de documento: Article