Multi-Targeted Molecular Docking and Drug-Likeness Evaluation of some Nitrogen Heterocyclic Compounds Targeting Proteins Involved in the Development of COVID-19.

Hui, Lok Yong; Mun, Chan Sook; Sing, Lai Cong; Rajak, Harish; Karunakaran, Rohini; Ravichandran, Veerasamy

Hui, Lok Yong; Mun, Chan Sook; Sing, Lai Cong; Rajak, Harish; Karunakaran, Rohini; Ravichandran, Veerasamy.

Afiliação

Hui LY; Pharmaceutical Chemistry, Faculty of Pharmacy; AIMST University, Semeling-08100, Bedong, Malaysia.
Mun CS; Pharmaceutical Chemistry, Faculty of Pharmacy; AIMST University, Semeling-08100, Bedong, Malaysia.
Sing LC; Pharmaceutical Chemistry, Faculty of Pharmacy; AIMST University, Semeling-08100, Bedong, Malaysia.
Rajak H; SLT Institute of Pharmaceutical Sciences, Guru Ghasidas University, Bilaspur, India.
Karunakaran R; Faculty of Medicine, AIMST University, Semeling-08100, Kedah, Malaysia.
Ravichandran V; Centre of Excellence for Biomaterials Sciences, AIMST University, Semeling-08100, Bedong, Malaysia.

Med Chem ; 19(3): 297-309, 2023.

Article em En | MEDLINE | ID: mdl-35713125

Assuntos

COVID-19; Compostos Heterocíclicos; Humanos; SARS-CoV-2; Simulação de Acoplamento Molecular; Tratamento Farmacológico da COVID-19; Hidroxicloroquina; Glicoproteína da Espícula de Coronavírus; Compostos Heterocíclicos/farmacologia; RNA Polimerase Dependente de RNA; Simulação de Dinâmica Molecular; Antivirais/farmacologia

Palavras-chave

Coronavirus disease-19; SARS-CoV-2; molecular docking; multitarget; nitrogen heterocyclics; pneumonia outbreak

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 / Compostos Heterocíclicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: COVID-19 / Compostos Heterocíclicos Idioma: En Ano de publicação: 2023 Tipo de documento: Article