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Hyperinsulinemia Is Highly Associated With Markers of Hepatocytic Senescence in Two Independent Cohorts.
Meijnikman, Abraham S; van Olden, Casper C; Aydin, Ömrüm; Herrema, Hilde; Kaminska, Dorota; Lappa, Dimitra; Männistö, Ville; Tremaroli, Valentina; Olofsson, Louise E; de Brauw, Maurits; van de Laar, Arnold; Verheij, Joanne; Gerdes, Victor E A; Schwartz, Thue W; Nielsen, Jens; Bäckhed, Fredrik; Pajukanta, Päivi; Pihlajamäki, Jussi; Tchkonia, Tamar; Kirkland, James L; Kuipers, Folkert; Nieuwdorp, Max; Groen, Albert K.
Afiliação
  • Meijnikman AS; Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.
  • van Olden CC; Department of Surgery, Spaarne Hospital, Hoofddorp, the Netherlands.
  • Aydin Ö; Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.
  • Herrema H; Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.
  • Kaminska D; Department of Surgery, Spaarne Hospital, Hoofddorp, the Netherlands.
  • Lappa D; Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.
  • Männistö V; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
  • Tremaroli V; Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Olofsson LE; Department of Medicine, Endocrinology and Clinical Nutrition, Kuopio University Hospital, Kuopio Finland.
  • de Brauw M; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • van de Laar A; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Verheij J; Department of Surgery, Spaarne Hospital, Hoofddorp, the Netherlands.
  • Gerdes VEA; Department of Surgery, Spaarne Hospital, Hoofddorp, the Netherlands.
  • Schwartz TW; Department of Pathology, University Medical Centers, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Nielsen J; Departments of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, the Netherlands.
  • Bäckhed F; Department of Surgery, Spaarne Hospital, Hoofddorp, the Netherlands.
  • Pajukanta P; Laboratory for Molecular Pharmacology, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pihlajamäki J; Systems and Synthetic Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
  • Tchkonia T; Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Kirkland JL; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kuipers F; Region Västra Götaland, Department of Clinical Physiology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Nieuwdorp M; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA.
  • Groen AK; Institute for Precision Health, David Geffen School of Medicine at UCLA, Los Angeles, CA.
Diabetes ; 71(9): 1929-1936, 2022 09 01.
Article em En | MEDLINE | ID: mdl-35713877

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Hepatopatia Gordurosa não Alcoólica / Hiperinsulinismo Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Hepatopatia Gordurosa não Alcoólica / Hiperinsulinismo Idioma: En Ano de publicação: 2022 Tipo de documento: Article