Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition.

Conciatori, Fabiana; Salvati, Erica; Ciuffreda, Ludovica; Shirasawa, Senji; Falcone, Italia; Cognetti, Francesco; Ferretti, Gianluigi; Zeuli, Massimo; Del Bufalo, Donatella; Bazzichetto, Chiara; Milella, Michele.

Afiliação

Conciatori F; Medical Oncology 1, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Salvati E; Preclinical Models and New Therapeutic Agents Unit, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Ciuffreda L; Institute of Molecular Biology and Pathology -National Research Council (BPM-CNR), Rome, Italy.
Shirasawa S; Department of Research, Advanced Diagnostics, and Technological Innovation (SAFU), Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Falcone I; Central Research Institute for Advanced Molecular Medicine, Fukuoka University, Fukuoka, Japan.
Cognetti F; Department of Research, Advanced Diagnostics, and Technological Innovation (SAFU), Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Ferretti G; Medical Oncology 1, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Zeuli M; Medical Oncology 1, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Del Bufalo D; Medical Oncology 1, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Bazzichetto C; Preclinical Models and New Therapeutic Agents Unit, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.
Milella M; Medical Oncology 1, Regina Elena National Cancer Institute (IRCCS), Rome, Italy.