Pictet-Spengler Reaction for the Chemical Synthesis of Strictosidine.
Methods Mol Biol
; 2505: 79-85, 2022.
Article
em En
| MEDLINE
| ID: mdl-35732938
ABSTRACT
Strictosidine is the common biosynthetic precursor of Monoterpene Indole Alkaloids (MIA). A practical single-step procedure to assemble strictosidine from secologanin is described via a bioinspired Pictet-Spengler reaction. Mild conditions and purification by crystallization and flash chromatography allow access to the targeted product in fair yield.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Alcaloides de Vinca
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article