New antivirals exploit viral feedback tricks for a cure without resistance.
Cell
; 185(13): 2210-2212, 2022 06 23.
Article
em En
| MEDLINE
| ID: mdl-35750032
ABSTRACT
Many approved drugs, including antivirals, are small-molecule inhibitors of disease-causing proteins. Such inhibitors often elicit resistance during treatment. Chaturvedi et al. propose new, feedback-disruptor (FD) antivirals that efficiently cure infected cells from viruses and minimize the chance of resistance, providing a new paradigm to treat viral infections and possibly other diseases.
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1
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Viroses
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article