Demineralized human dentin matrix for alveolar ridge preservation using a volumetric and histologic analyses in rats.
Braz Dent J
; 33(3): 82-91, 2022.
Article
em En
| MEDLINE
| ID: mdl-35766721
ABSTRACT
The aim of this study was to evaluate a Demineralized Human Dentine Matrix (DHDM) as viable biomaterial for alveolar ridge preservation in a rat model. Wistar rats were submitted to the extraction of maxillary first molars bilaterally. Sockets were filled with biomaterials and divided into 4 experimental groups (n=5) blood clot, autogenous bone, bovine-derived xenograft (BDX) and DHDM. Animals were sacrificed at 7, 14 e 28 days. Microtomography (uCT) volumetric evaluation and qualitative histological analyses were performed. Results obtained through the uCT showed similar values between the DHDM and the other experimental groups. The histological evaluation demonstrated DHDM with an unspecific inflammatory process and bone neoformation with slow reabsorption of the material. This result indicates that DHDM implanted in rat sockets is biocompatible and reduces the alveolar ridge volume loss after tooth extraction.
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Base de dados:
MEDLINE
Assunto principal:
Perda do Osso Alveolar
/
Alvéolo Dental
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article