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Streptocinnamides A and B, Depsipeptides from Streptomyces sp. KMM 9044.
Makarieva, Tatyana N; Romanenko, Lyudmila A; Mineev, Konstantin S; Shubina, Larisa K; Guglya, Elena B; Kalinovskaya, Natalia I; Ivanchina, Natalia V; Guzii, Alla G; Belozerova, Olga A; Kovalchuk, Sergey I; Popov, Roman S; Denisenko, Vladimir A; Mikhailov, Valery V; Babenko, Vladislav V; Ilina, Elena N; Malakhova, Maja V; Terekhov, Stanislav S; Kudzhaev, Arsen M; Dmitrenok, Pavel S; Yampolsky, Ilia V; Stonik, Valentin A.
Afiliação
  • Makarieva TN; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Romanenko LA; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Mineev KS; Pirogov Russian National Research Medical University, Ostrovitianov 1, 117997 Moscow, Russia.
  • Shubina LK; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, GSP-7, Ulitsa Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.
  • Guglya EB; Moscow Institute of Physics and Technology, Institutskiy per. 9, 141701 Dolgoprudny, Moscow Region, Russia.
  • Kalinovskaya NI; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Ivanchina NV; Pirogov Russian National Research Medical University, Ostrovitianov 1, 117997 Moscow, Russia.
  • Guzii AG; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, GSP-7, Ulitsa Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.
  • Belozerova OA; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Kovalchuk SI; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Popov RS; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Denisenko VA; Pirogov Russian National Research Medical University, Ostrovitianov 1, 117997 Moscow, Russia.
  • Mikhailov VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, GSP-7, Ulitsa Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.
  • Babenko VV; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, GSP-7, Ulitsa Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.
  • Ilina EN; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Malakhova MV; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Terekhov SS; G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Prospect 100-let Vladivostoku 159, 690022 Vladivostok, Russia.
  • Kudzhaev AM; Federal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, Malaya Pirogovskaya 1a, 119435 Moscow, Russia.
  • Dmitrenok PS; Federal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, Malaya Pirogovskaya 1a, 119435 Moscow, Russia.
  • Yampolsky IV; Federal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, Malaya Pirogovskaya 1a, 119435 Moscow, Russia.
  • Stonik VA; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, GSP-7, Ulitsa Miklukho-Maklaya, 16/10, 117997 Moscow, Russia.
Org Lett ; 24(27): 4892-4895, 2022 07 15.
Article em En | MEDLINE | ID: mdl-35770905
ABSTRACT
The bacterium Streptomyces sp. KMM 9044 from a sample of marine sediment collected in the northwestern part of the Sea of Japan produces highly chlorinated depsiheptapeptides streptocinnamides A (1) and B (2), representatives of a new structural group of antibiotics. The structures of 1 and 2 were determined using nuclear magnetic resonance and mass spectrometry studies and confirmed by a series of chemical transformations. Streptocinnamide A potently inhibits Micrococcus sp. KMM 1467, Arthrobacter sp. ATCC 21022, and Mycobacterium smegmatis MC2 155.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Depsipeptídeos Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Streptomyces / Depsipeptídeos Idioma: En Ano de publicação: 2022 Tipo de documento: Article